Pontotoc is a city in, and the county seat of, Pontotoc County, Mississippi, located to the west of the much larger city of Tupelo. The population was 5,625 at the 2010 census.
According to the United States Census Bureau, the city has a total area of 9.6 sq mi (25 km), of which 9.4 sq mi (24 km) is land and 0.2 sq mi (0.52 km) (1.66%) is covered by water.
As of the census of 2010, 5,625 people, 2,325 households, and 2,129 families resided in the city. The population density was 555.9 people per square mile (214.6/km²). The 2,250 housing units averaged 238.1/sq mi (91.9/km²). The racial makeup of the city was 70.08% White, 20.42% African American, 0.35% Native American, 0.24% Asian, 0.03% Pacific Islander, 7.39% from other races, and 1.45% from two or more races. Hispanics of any race were 2.76% of the population.
Of the 2,325 households, 32.2% had children under the age of 18 living with them, 49.1% were married couples living together, 16.0% had a female householder with no husband present, and 31.9% were not families. About 29.2% of all households were made up of individuals, and 15.5% had someone living alone who was 65 years of age or older. The average household size was 2.41, and the average family size was 2.97.
In the city, the population was distributed as 25.7% under the age of 18, 8.6% from 18 to 24, 26.3% from 25 to 44, 21.5% from 45 to 64, and 18.0% who were 65 years of age or older. The median age was 37 years. For every 100 females, there were 84.8 males. For every 100 females age 18 and over, there were 77.6 males.
The median income for a household in the city was $28,491, and for a family was $39,306. Males had a median income of $31,403 versus $23,491 for females. The per capita income for the city was $17,324. About 12.0% of families and 17.6% of the population were below the poverty line, including 18.5% of those under age 18 and 23.0% of those age 65 or over.
Pontotoc Mississippi neighborhoods include: Hardin Cir, Meadowlark, N Main St – E Oxford St, Tall Oaks, Troy